EE 385J: Topics in Biomedical Engineering

Three lecture hours a week for one semester, or as required by the topic. May be repeated for credit when the topics vary.


Topic: 3 - Bioelectric Phenomena Same as Biomedical Engineering 384J (Topic 4: Bioelectric Phenomena). Examines the physiological bases of bioelectricity and the techniques required to record bioelectric phenomena both intracellularly and extracellularly; the representation of bioelectric activity by equivalent dipoles and the volume conductor fields produced. Topic: 9 - Laser-Tissue Interaction: Thermal Same as Biomedical Engineering 381J (Topic 1: Laser-Tissue Interaction: Thermal). The thermal response of random media in interaction with laser irradiation. Calculation of the rate of heat production caused by direct absorption of the laser light, thermal damage, and ablation. Topic: 15 - Biosignal Analysis Same as Biomedical Engineering 384J (Topic 3: Biosignal Analysis). Theory and classification of biological signals such as EEG, EKG, and EMG. Data acquisition and analysis procedures for biological signals, including computer applications. Topic: 16 - Laser-Tissue Interaction: Optical Same as Biomedical Engineering 381J (Topic 2: Laser-Tissue Interaction: Optical). The optical behavior of random media such as tissue in interaction with laser irradiation. Approximate transport equation methods to predict the absorption and scattering parameters of laser light inside tissue. Port-wine stain treatment; cancer treatment by photochemotherapy; and cardiovascular applications. Topic: 17 - Biomedical Instrumentation II: Real-Time Computer-Based Systems Same as Biomedical Engineering 384J (Topic 2: Biomedical Instrumentation II: Real-Time Computer-Based Systems). Design, testing, patient safety, electrical noise, biomedical measurement transducers, therapeutics, instrumentation electronics, microcomputer interfaces, and embedded systems. Four structured laboratories and an individual project laboratory. Topic: 18 - Biomedical Imaging: Signals and Systems Same as Biomedical Engineering 381J (Topic 3: Biomedical Imaging: Signals and Systems). Physical principles and signal processing techniques used in thermographic, ultrasonic, and radiographic imaging, including image reconstruction from projections such as CT scanning, MRI, and millimeter wave determination of temperature profiles. Additional prerequisite: Electrical Engineering 371R. Topic: 23 - Optical Spectroscopy Same as Biomedical Engineering 381J (Topic 4: Optical Spectroscopy). Measurement and interpretation of spectra: steady-state and time-resolved absorption, fluorescence, phosphorescence, and Raman spectroscopy in the ultraviolet, visible, and infrared portions of the spectrum. Topic: 26 - Therapeutic Heating Same as Biomedical Engineering 381J (Topic 5: Therapeutic Heating). Engineering aspects of electromagnetic fields that have therapeutic applications: diathermy (short wave, microwave, and ultrasound), electrosurgery (thermal damage processes), stimulation of excitable tissue, and electrical safety. Topic: 28 - Noninvasive Optical Tomography Same as Biomedical Engineering 381J (Topic 6: Noninvasive Optical Tomography). Basic principles of optical tomographic imaging of biological materials for diagnostic or therapeutic applications. Optical-based tomographic imaging techniques including photothermal, photoacoustic, and coherent methodologies. Topic: 31 - Biomedical Instrumentation I Same as Biomedical Engineering 384J (Topic 1: Biomedical Instrumentation I). Application of electrical engineering techniques to analysis and instrumentation in biological sciences: pressure, flow, temperature measurement; bioelectrical signals; pacemakers; ultrasonics; electrical safety; electrotherapeutics. Topic: 32 - Projects in Biomedical Engineering Same as Biomedical Engineering 384J (Topic 5: Projects in Biomedical Engineering). An in-depth examination of selected topics, such as optical and thermal properties of laser interaction with tissue; measurement of perfusion in the microvascular system; diagnostic imaging; interaction of living systems with electromagnetic fields; robotic surgical tools; ophthalmic instrumentation; noninvasive cardiovascular measurements. Three lecture hours and six laboratory hours a week for one semester. Additional prerequisite: Electrical Engineering 385J (Topic 31). Topic: 33 - Neurophysiology/Prosthesis Design Same as Biomedical Engineering 384J (Topic 6: Neurophysiology/Prosthesis Design). The structure and function of the human brain. Discussion of selected neurological diseases in conjunction with normal neurophysiology. Study of neuroprosthesis treatments and design philosophy, functional neural stimulation, and functional muscular stimulation.

Course Level: 



Graduate standing in engineering and consent of instructor.